Taking tramadol with other medicines and herbal supplements (2024)

FAQs

Can I take supplements with tramadol? ›

No interactions were found between Daily Multi-Vitamins with Minerals and tramadol. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Tramadol should not be used in combination with MAO inhibitors or serotonin-precursors (such as L-tryptophan, oxitriptan) and should be used with caution in combination with other serotonergic drugs (triptans, certain tricyclic antidepressants, lithium, St. John's Wort) due to the risk of serotonin syndrome.

Important. Do not take medicines called monoamine oxidase inhibitors or MAOIs (which are used to treat depression) with tramadol. The combination can cause significant side effects such as anxiety, confusion and hallucinations.

Tramadol and acetaminophen combination is used to relieve acute pain severe enough to require an opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. When used together, the combination provides better pain relief than either medicine used alone.

Interaction of tramadol with magnesium is potent and effective. This is a safe combination for preemptive, and in particular for an emptive strategy to treat pain associated with inflammation.

Do not drink any alcohol as this will make you feel more tired. Stick to simple meals and do not eat rich or spicy food. It might help to take your tramadol after you've eaten a meal or snack. If you're being sick, try small frequent sips of water.

For patients at a high risk of hip fracture, those aged more than 60 years (especially those aged 60–70 years), and those who are male, tramadol for long-term continuous use should only be prescribed with caution.

Recently, several studies have been conducted to prove that the combination of tramadol with a Non-Steroidal Anti-Inflammatory Drug, such as ibuprofen, can provide an effect that is better than each drug has when taken alone.

Therefore, the results of this study revealed the ability of caffeine to potentiate the anti-nociceptive effect of tramadol, being capable of causing synergism with this opioid drug, which is broadly used in moderate–severe pain management.

When should tramadol be avoided? ›

Long term utilization of tramadol is associated with various neurological disorders like seizures, serotonin syndrome, Alzheimer's disease and Parkinson's disease. Tramadol produces seizures through inhibition of nitric oxide, serotonin reuptake and inhibitory effects on GABA receptors.

Results: Naloxone reversed tramadol-induced respiratory depression (p < . 05) but significantly increased seizures (p < . 01) and prolonged their occurrence time. Diazepam abolished seizures but significantly deepened rat sedation (p < .

Oxycodone and tramadol are two prescription opioid medications used to help relieve pain. Even though these medications have a similar use, oxycodone is known to be more potent, with stronger pain-relieving capabilities than tramadol. The FDA classifies oxycodone as a higher risk for misuse than tramadol.

Tramadol 50 mg may be adequate as the initial dose for moderate pain. For moderate to severe pain, 50 - 100 mg as needed for relief, every four to six hours may be administered. Tramadol 100mg is usually more effective as the initial dose for more severe pain. The maximum daily dose should not exceed 400mg per day.

Recently, several studies have been conducted to prove that the combination of tramadol with a Non-Steroidal Anti-Inflammatory Drug, such as ibuprofen, can provide an effect that is better than each drug has when taken alone.

Interactions between your drugs

No interactions were found between caffeine and tramadol.

Also, other experiments indicated that tramadol causes the alpha-1 adrenergic receptors to increase in density in the brain cortex and results in upregulation of dopaminergic receptors in the nucleus accumbens which has important functions in motivational behaviour [29].

Tramadol is an opioid pain medication. It doesn't cause damage to the liver or kidneys at normal doses. But high doses, long-term use, and drug interactions can increase the risk. And if you already have liver or kidney issues, your risk of side effects goes up.